HPA axisPending Verification
Type: framework Aliases: hypothalamic-pituitary-adrenal axisstress axis
- Systems Analogy A home thermostat connecting temperature sensors directly to the basement furnace to regulate heating cycles.
- Formal Definition The hypothalamic-pituitary-adrenal neuroendocrine feedback circuit regulating physiological stress responses, cortisol secretion, and metabolic adaptation.
Mentioned In
Scientific Sources & Literature Citations
- [1] Empirical Study Smith SM, Vale WW. The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin Neurosci. 2006;8(4):383-395. ↗
"The hypothalamic-pituitary-adrenal axis is a major neuroendocrine system that controls reactions to stress and regulates many body processes."