amyloid-beta
Type: protein Aliases: amyloid plaquesbeta-amyloidAβ
- Systems Analogy Sticky protein clumps that pile up between brain cells and disrupt normal brain communication.
- Formal Definition A protein peptide that can accumulate in the brain, forming sticky plaques associated with neurodegeneration and Alzheimer's disease progression.
Mentioned In
Scientific Sources & Literature Citations
- [1] Empirical Study Selkoe DJ, Hardy J. The amyloid hypothesis of Alzheimer's disease at 25 years. EMBO Mol Med. 2016;8(6):595-608. ↗
"The accumulation of amyloid-beta peptides in the cerebral cortex is a critical early event in the pathogenesis of Alzheimer's disease."