AMPK
AMP-activated protein kinase; a conserved master energy sensor that regulates glucose and lipid meta...
APOE4
Apolipoprotein E4; the strongest genetic risk factor allele for sporadic Alzheimer's disease, linked...
Nrf2
Nuclear factor erythroid 2-related factor 2; a Nuclear factor that coordinates the gene expression o...
A DNA-binding transcription factor protein that translocates to the cell nucleus to control transcri...
SIRT1
Sirtuin 1; an NAD+-dependent protein deacetylase that acts as a key metabolic sensor regulating chro...
TLR4
Toll-like receptor 4; a cell-surface pattern recognition receptor that binds to bacterial LPS and tr...
A protein peptide that can accumulate in the brain, forming sticky plaques associated with neurodege...
kinase
An enzyme that catalyzes the transfer of a phosphate group from ATP to a specific substrate molecule...
tau
A microtubule-associated protein synthesized in neurons that stabilizes axonal structures, whose hyp...
