blood-brain barrier
Type: concept Aliases: BBB blood-brain barrier integrity blood-brain barrier transport
Systems Analogy
A high-security customs border control post at an international port that inspects every incoming cargo crate before admitting it to the capital.
A highly selective semipermeable membrane border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system.
Mentioned In
Scientific Sources & Verbatim Definitions
- Empirical StudyYassine HN, et al. CNS target engagement of high-dose DHA supplementation in older adults at risk for dementia. eBioMedicine. 2026;106:106316. ↗
"The blood-brain barrier regulates chemical transport to ensure optimal CNS homeostasis."