gut-brain axis
Type: process Aliases: gut-braingut-microglia axisgut-brain pathwaygut-brain axis communication
- Systems Analogy A direct two-way communication hotline connecting your gut and your brain.
- Formal Definition The bidirectional biochemical communication network linking the gastrointestinal tract and its resident microbiota with the central nervous system.
Mentioned In
- Biological CircuitsFasting, Microbiome Shifts, and Neuroinflammation, Luteolin Gut-Brain Kynurenine Axis
- Organismmicrobiota, microglia
- ProcessAlternate Day Fasting, cognitive function, FMT, neuroinflammation
Scientific Sources & Literature Citations
- [1] Empirical Study Mela V, et al. Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis. Gut. 2025;74:1828-1846. ↗
"These results establish the gut-brain axis as a key pathway through which diet-induced microbiome shifts modulate microglia."