neurofibrillary
Type: condition Aliases: neurofibrillary tanglestangles
- Systems Analogy Tangled clusters of twisted fibers inside brain cells that disrupt normal cellular messaging.
- Formal Definition Relating to neurofibrillary tangles; pathological aggregates of hyperphosphorylated tau protein found inside neurons in Alzheimer's disease.
Mentioned In
- Proteintau
Scientific Sources & Literature Citations
- [1] Empirical Study Kandel ER, et al. Principles of Neural Science. 6th ed. 2021. ↗
"Neurofibrillary tangles correlate with neurodegeneration and cognitive decline."