tau
Type: protein Aliases: tau proteintau phosphorylation
- Systems Analogy Internal structural ties that keep brain cell tracks straight, causing blockages when tangled.
- Formal Definition A microtubule-associated protein synthesized in neurons that stabilizes axonal structures, whose hyperphosphorylation drives neurofibrillary tangles.
Mentioned In
- Biological CircuitsGlymphatic Clearance during Slow-Wave Sleep, Periodontal Pathology and Alzheimer's Link
- Conditionneurofibrillary
- Moleculegingipains, microtubule
Scientific Sources & Literature Citations
- [1] Empirical Study Kandel ER, et al. Principles of Neural Science. 6th ed. 2021. ↗
"Tau protein binds and stabilizes microtubules in axonal compartments."