LPS
Type: molecule Aliases: lipopolysaccharide endotoxin
Systems Analogy
Toxic exhaust soot leaking from surrounding factory chimneys that triggers regional security alarms.
Lipopolysaccharide; a major component of the outer membrane of Gram-negative bacteria that acts as a potent endotoxin, inducing microglial activation and systemic inflammatory cascades.
Scientific Sources & Verbatim Definitions
- Empirical StudyZhan X, et al. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016;87(22):2324-2332. ↗
"Lipopolysaccharide (LPS) is a component of Gram-negative bacterial outer membrane that acts as an endotoxin to induce microglial activation."